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      Cavro®
      Air Displacement Pipettor (ADP)

      A compact pipetting solution for molecular and cell biology applications

       
      Overview
      Go to Shop       Talk to an expert




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      Tab 01 / Overview
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      A compact, pneumatic pipetting solution
      for OEM instrumentation

      The Cavro ADP is one of the smallest and most sophisticated air pipettors on the market, combining advanced pipetting, process security and tip eject functionalities in a single unit.

      Designed for easy integration into compact instruments,  this pipetting module is ideal for applications that use disposable tips to prevent carry-over or contamination, such as molecular diagnostics, cell culturing and point of care (POC) diagnostics.

      It offers high performance liquid handling with improved process security – including pressure-based liquid level detection, tip presence confirmation and pressure data streaming – simplified workflows and lower integration requirements.

      ADP Detect Mode offers enhanced process security for those looking for an off-the-shelf process security solution that is easy to integrate into a new or existing instrument.

      The ADP is easily integrated into compact instruments using an optional z-axis or one of your own design, with a slim profile to allow 18 mm tip-to-tip spacing for microplate-based applications in diagnostics, genomics and immunochemistry.

      Highlights

      • Outstanding pipetting performance
      • Highly programmable feature set
      • Integrated process security

      Fully programmable pneumatic pipetting

      The Cavro ADP is a fully programmable pipetting module that uses air rather than liquid displacement to aspirate and dispense fluids. Air displacement pipetting simplifies your instrument design and reduces costs by eliminating system liquids and associated components such as pumps, degassers, tubing, fittings, valves, etc.

      This Cavro ADP’s slender design makes it ideal for POC applications, and it is compatible with Tecan’s high quality disposable tips to reduce carry-over and provide precise dispensing.

      Read more

      Excellent pipetting performance

      Pipetting performance is comparable to advanced manual pipettors, using a range of disposable tip sizes. The Cavro ADP is factory calibrated to ensure accurate air displacement and minimize pump-to-pump variability.

      The pipettor’s validated design will help to simplify your development projects, while its excellent reliability will ensure uninterrupted operation of your instrument.

      Read more

      ADP Detect Mode

      ADP Detect Mode improves process security by monitoring and analyzing the pressure during aspiration steps.

      It identifies irregularities in the pressure signal during aspiration, typically caused by disturbances such as an empty well, the tip leaving the liquid prematurely, or blockage of the tip orifice.

      Maintenance-free design

      The maintenance-free design of the Cavro ADP simplifies system integration and reduces maintenance costs compared to alternative pipetting technologies.

      The air-displacement pipetting mechanism includes onboard liquid level detection and diagnostics to monitor correct operation. The Cavro ADP can be integrated with any z-axis to fit your system architecture

      Software

      The ADP is supported with Cavro integration kit or Cavro Fusion Software for rapid and easy setup and evaluation with other Cavro components.

      Cavro Integration Kit
      Cavro Fusion Software

      Liquid level detection

      The Cavro ADP features built-in pressure-based liquid level detection (pLLD) with user configurable settings. Data from the pressure sensor can also be streamed in real-time to enable other pressure monitoring tasks via a host computer, such as blockage or bubble detection.

      In addition, the Cavro ADP is compatible with external capacitive liquid level detection (cLLD) technologies (cLLD sensor board available separately), ensuring maximum flexibility for your instrument design.

      Tip sensor

      The pipettor features an integrated disposable tip sensor to support sample integrity and process security requirements.

      Its firmware can determine if a disposable tip has not been picked up or has fallen off the probe, flagging and logging any errors.

      Tip ejector

      A disposable tip ejection mechanism is incorporated into the design of the Cavro ADP, allowing tips to be ejected by a single command.

      The ejector uses the same drive mechanism as the plunger, minimizing weight and further simplifying integration.




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      Tab 02 / Options
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      Configurations

        ADP ordering part numbers
      Cavro Standard Air Displacement Pipettor (includes pressure sensor, tip eject, tip detection) 30041734
      Cavro ADP Detect (process security via Detect Algorithm + pressure sensor, tip eject, tip detection) 30183817
      Cavro Air Displacement Pipettor (ADP) Starter Kit 30162556

      Disposable tip options

        Tecan Standard Tecan Pure Tecan Sterile
      Application examples
      customer segments      		 ELISA: Sample handling,
      Biochemical screening      		 Genomics research:
      Forensics, Molecular Diagnostics      		 Cell biology, Microbiology
      Cell-based screening
      Features Non-filtered Filtered Non-filtered Filtered Non-filtered Filtered
      10 µl      
      Conductive      		  
      Conductive      		  
      Conductive      		  
      Conductive
      50 µl          
      Conductive      		  
      Conductive
      200 µl      
      Conductive      		  
      Conductive      		  
      Conductive      		  
      Conductive
      1000 µl    
      Conductive      		  
      Conductive      		  
      Conductive      		  
      Conductive      		  
      Conductive

      Please click here for more details on configurations and options.




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      Tab 03 / Specifications
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      Plunger drive
      Principle Stepper motor gear driven piston, integrated encoder for step loss detection
      Travel 50 mm
      Plunger speed1 1.0 sec to >10 h
      Resolution 40,000 increments
      (25 nl/increment)
      Life expectancy Drive mechanism: 5 million cycles
      Probe assembly: 1 million cycles (field replaceable)

      1) per stroke, depending on syringe size and tubing

      Syringes
      Sizes N/A
      Barrel material N/A
      Plunger seal material N/A
      Precision1 ≤0.75 % at 1,000 μl
      ≤6 % at at 1 μl
      Accuracy2 ≤1 % at 1,000 μl
      ≤5 % at 1 μl

      1) % CV at room temperature using deionized water
      2) % deviation at room temperature using deionized water

      Dimensions
      Height 141 mm (body)
      Probe + tip length: ~100 mm
      Width ~17 mm (18 mm device spacing)
      Depth 85 mm
      Weight <500 g (1.1 lb)
      Power requirements
      Supply voltage 24 VDC ± 10 %
      Peak current 500 mA
      Interface
      Type RS-485 or CAN BUS
      Baud rate RS-485: 9,600,38,400 or 115,200 (default)
      CAN: 100 KB, 125 KB, 250 KB, 500 KB (default) or 1 MB
      Plunger speed1 1.0 sec to >10 h
      Addressing Up to 8 devices can be addressed individually
      Communications Data terminal and OEM protocol (Serial); Cavro CAN (CAN)
      Inputs One TTL Level Input
      Outputs One TTL Level Output

      1) per stroke, depending on syringe size and tubing

      Firmware
        Cavro's industry standard OEM command set including volume-based pipetting commands, complete programming and speed control, error handling and diagnostics.
      Environmental
      Operating temperature1 15-35 °C
      (59-95 °F)
      Humidity2 20-85 % RH at 35 °C
      Storage temperature -20 to +70 °C
      (-4 to 158 °F)

      1) mechanism
      2) non-condensing, mechanism

      Please click here for more specifications.




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      Tab 04 / Videos
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      Videos

      Cavro® ADP Detect

      The Cavro ADP Detect combines aspiration pressure monitoring with onboard cLLD to increase reliability. This allows the module to quickly and accurately identify any signal irregularities during aspiration, easily detecting a wide range of situations. This offers instrument designers more flexibility in terms of process control and error handling, allowing them to choose the detection method that is optimal for specific situations of sample type.

      Cavro® Air Displacement Pipettor

      The Cavro ADP is one of the smallest and most sophisticated air pipettors on the market, combining advanced pipetting, process security and tip eject functionalities in a single unit.Designed for easy integration into compact instruments, this pipetting module is ideal for applications that use disposable tips to prevent carry-over or contamination, such as molecular diagnostics, cell culturing and point of care (POC) diagnostics.

      The Cavro Air Displacement Pipettor (ADP) Starter Kit is a ready-to-use kit

      This video provides step-by-step instrudtons on setting up your Cavro ADP - one of the smallest and most sophisticated air pipettors on the market, combining advanced pipetting, process security and disposable tip eject functionalities in a single unit.

      The Encompass MDX: rapid development of a molecular diagnostics platform to address diverse market needs

      Video presentation at Tecan booth at AACC 2016. Presenters: Steve Pemberton, VP of Marketing and Sales at Rheonix; William Hathaway, Manager of Product Engineering at Rheonix

      Cavro ADP a hit with Chinese in vitro diagnostic customers

      Chinese company DaAn Gene has integrated the Cavro ADP and disposable tips into its new generation of molecular diagnostic instruments, bringing the advantages of Tecan’s liquid pipetting expertise to blood banks and infectious disease laboratories in China.

      Play this video in Chinese

      Read more




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      Tab 05 / Literature
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      Brochures

      Cavro Air Displacement Pipettor

      The Cavro Air Displacment Pipettor automates routine pipetting tasks with accuracy and precision, and is designed to streamline your automation requirements.

      Cavro Air Displacement Pipettor Detect

      The Cavro Air Displacement Pipettor Detect offers the same look and excellent air displacement pipetting performance with enhanced process security for even greater piece of mind.

      Quick start guides

      Pipetting with the Cavro ADP

      This Quick Start Guide offers helpful tips and techniques to help you accelerate and optimize your liquid handling techniques with the Cavro ADP.

      Cavro ADP and pressure streaming

      This Quick Start Guide describes how to capture, understand and use streamed pressure data to get the most value from your pipettor.

      Cavro ADP electromechanical integration

      This Quick Start Guide offers helpful tips and techniques to connect to and communicate with the Cavro ADP.

      Cavro ADP and liquid level detection

      This Quick Start Guide offers tips and techniques to help Cavro ADP customers use its built-in liquid level detection to improve process security in their applications.

      Tecan Journal Articles

      Cavro ADP – a new innovation for liquid handling
      [TJ 01/2011]

      The Cavro Air Displacement Pipettor (ADP) is a compact pipetting solution for easy integration and exceptional liquid handling performance.

      Cavro ADP a hit with Chinese in vitro diagnostic customers
      [TJ 03/2015]

      Chinese company DaAn Gene has integrated the Cavro ADP into its new generation of molecular diagnostic instruments, bringing the advantages of Tecan’s liquid pipetting expertise to blood banks and infectious disease laboratories in China.

      Extended flexibility of Cavro® Omni Robot
      [TJ 01/2014]

      Tecan has introduced two extra options for the Cavro Omni Robot; the Dual Z and the ADP (Air Displacement Pipettor).
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      Literature

       

       

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